Huntington's disease - the underlying causes

Huntington's disease - the underlying causes

Why is Huntington's disease developing?

Huntington's disease is a rare, inherited disease that causes the progressive breakdown (degeneration) of nerve cells in the brain.

Huntington's disease has a wide impact on a person's functional abilities and usually results in movement, thinking (cognitive) and psychiatric disorders.

Diagnosis is common in people aged 30 to 50 years.

It is impossible to prevent the risk of impairment of physical, mental and behavioral skills, although with medication therapy it is possible to manage certain symptoms.

Causes

Huntington's disease is caused by an inherited difference in a single gene. Huntington's disease is an autosomal dominant disorder, which means that a person needs only one copy of the nontypical gene to develop the disorder.

After Huntington's disease starts, a person's functional abilities gradually worsen over time.

The rate of disease progression and duration varies.

The mental health of the patient is very important, because this disease is often accompanied by depression, therefore, the person must remain under the supervision of a psychologist.

Eventually, a person with Huntington's disease requires help with all activities of daily living and care. Late in the disease, the person will likely be confined to a bed and unable to speak.

Someone with Huntington's disease is generally able to understand language and has an awareness of family and friends, though some won't recognize family members.

Source:
https://www.mayoclinic.org/diseases-conditions/huntingtons-disease/symptoms-
causes/syc-20356117